Repro steps:
1. Open attached project
2. Build and Run on Android
3. Click the huge button twice to change the resolution
4. Rotate phone to the left to change screen orientation to left landscape
5. Attempt to click the huge button on the right side of the screen

Expected: The button is pressable and changes the resolution when pressed
Actual: The button cannot be pressed on the right side of the screen. When rotated back to Portrait Mode the button can't be pressed on the bottom half of the screen

Reproducible with: 2017.4.13f1, 2018.2.13f1, 2018.3.0b6, 2019.1.0a5

DUT:
Reproduced on:
VLNQA00137, Samsung Galaxy S9+ (SM-G965F), Android 8.0.0, CPU: Exynos 9 Series 9810, GPU: Mali-G72
VLNQA00144, Samsung Galaxy S9 (SM-G960U1), Android 8.0.0, CPU: Snapdragon 845 SDM845, GPU: Adreno (TM) 630
VLNQA00001, Google Pixel 2 (Pixel 2), Android 8.1.0, CPU: Snapdragon 835 MSM8998, GPU: Adreno (TM) 540

Didn't reproduce on:
VLNQA00155, Meizu PRO 7 Plus (PRO 7 Plus), Android 7.0, CPU: MediaTek Helio X30 MT6799, GPU: PowerVR Rogue Marlowe
VLNQA00178, Xiaomi Redmi Note 4 (Redmi Note 4), Android 6.0, CPU: MediaTek Helio X20 MT6797M, GPU: Mali-T880

Fixed in: 2019.1.0a7