Reproduction steps:
1. Open the attached “ReproProj” project
2. Open the “Assets/Scenes/SampleScene” scene
3. Enter the Play mode
4. Turn on the Profiler via Window -> Analysis -> Profiler
5. Set the Profiler to Play mode and record for a few seconds, then pause profiling (but stay in playmode)
6. Select the penultimate frame and observe the Timeline
7. Set the Profiler to Edit mode and record for a few seconds, then stop
8. Select the penultimate frame and observe the Timeline

Expected Result: The Edit mode frame should have a frame take about 90-100 ms the same as the Play mode
Actual Result: The Edit mode frame takes only about 20-30 ms

Reproducible with: 2021.2.0b13, 2021.2.0b17, 2021.2.19f1. 2021.3.40f1, 2022.3.35f1, 6000.0.8f1
Application.targetFrameRate is completely ignored (independent of Profiler target) on: 2021.2.0a2, through to 2021.2.0b12 
Not reproducible on: 2020.2.7f1, 2021.1.28f1, 2021.2.0a1.

Reproducible on: Windows 11 Pro
Not reproducible on: No other environments tested

Additional Notes:
- The time spend waiting for the Target Frame Rate is hidden within the Editor loop, which is not how it should be.
- It would be nice to know what the targetFrameRate and vSync settings for a frame where to more easily spot mistakes like the one in this script, which set the targetFrameRate to 10.
- Application.targetFrameRate remains set to 10 while profiling Edit Mode, the Editor just ignores it.