How to reproduce:
1. Open the attached project "SpriteMissing.zip"
2. Open LightBall_Basic prefab
3. Select Shield in the Hierarchy
4. Observe there is a sprite attached to the Sprite Renderer component
5. Exit Prefab View
6. Add the Prefab to a Scene
7. Select Shield in the Hierarchy

Expected result: There is a sprite attached to the Sprite Renderer component
Actual result: There is no sprite attached to the Sprite Renderer component

Reproducible with: 2021.2.0a4, 2021.2.0b2, 2022.1.0a1
Not reproducible with: 2018.4.34f1, 2019.4.28f1, 2020.3.14f1, 2021.1.13f1, 2021.2.0a3

Note:
1. Downgrading to a version where the issue is not reproducible and upgrading back fixes the problem