How to reproduce:
1. Open the attached “IN-103900” project
2. Open the “Scene” Scene
3. Ensure the Game Aspect Ratio is +not+ 4K UHD
4. Ensure Super Size is greater than 1 in the Inspector of the “Screenshot Maker” GameObject
5. Enter Play mode
6. Press [space] to capture a screenshot
7. Exit Play mode
8. Observe the result of "Screenshot.png" and compare it to "Expected Result.png" (Assets > Screenshots)

Expected result: "Screenshot.png" looks like "Expected Result.png"
Actual result: "Screenshot.png" has blocky artifacts

Reproducible with: 2022.1.0a1, 2022.3.63f1, 6000.0.51f1, 6000.1.7f1, 6000.2.0b5

Reproduced on: Windows 11
Not reproduced on: No other environment tested

Notes:
- Issue does not reproduce as noticeably when using Game Aspect Ratio 4K UHD
- Changing antialiasing settings does not change the amount of artifacting