Reproduction steps:

1. Open "MinimalReproProject"
2. Open the "Main" Scene
3. Navigate through the Project window to "Resources" -> "Color Schemes" -> "0.Color Scheme"
4. Change the "Red" to anything else
5. Reload the Scene
6. Notice that the color changed back to Red
7. Click on the "0.Color Scheme"

Expected Result: As the color of the Grid Objects is set in the "0.Color Scheme", the colors should change without having to save the scene
Actual Result: You have to save the scene to save the newly set color, even though it stays the same in the "0.Color Scheme"

Reproduced with: 2017.3.0a1, 2017.2.0b4
Did not reproduce on: 2017.1.0p1 (TileMap was not yet implemented)