Reproduction steps:
1. Open project "1322562.zip"
2. Open Scene "SampleScene"
3. Enter Play Mode
4. Open script "scr" in Visual Studio
5. Make sure the Console window is in view
6. Change the Debug.Log("no") to Debug.log("yes")
7. Save the script
8. Make sure Unity Editor is still out of focus and observe Console window

Expected result: "yes" is shown in the Console window
Actual result: "no" is shown in the Console window

Reproducible with: 2018.4.36f1, 2.0.9 (2020.1.0a1, 2020.3.14f1, 2021.1.14f1, 2021.2.0b3, 2022.1.0a1)
Not reproducible with: 2.0.9 (2019.4.29f1)