To reproduce: open the graphic test #697 in branch 'editor/bugfix/blurry-pixel-cache-regression'. Position any of the large "Alignment Setup" objects to an even + 0.5 (e.g. 98.5, 100.5, 102.5, etc). Observe the blurriness. This may be caused by the rounding difference between C++ and C#. See https://unity.slack.com/archives/C0QBL1TPZ/p1509119699000114

Once the issue is fixed, a graphic test case should be added to cover this issue and the new case should be documented properly.