Reproduction steps:
1. Open the attached project "IN-31619.zip"
2. Open the "scena" scene
3. Open the "space bg shader (Skybox)" shader graph
4. Add "Built-In" to Active Targets in the Graph Inspector
5. Click "Save Asset"
6. Return to the scene

Expected result: The scene does not change
Actual result: The scene changes

Reproducible with: 14.0.2 (2022.2.0a12), 14.0.6 (2022.2.10f1), 15.0.4 (2023.1.0b7), 16.0.0 (2023.2.0a5)
Not reproducible with: 10.10.1 (2020.3.46f1), 12.1.10 (2021.2.10f1), 14.0.2 (2022.2.0a11)

Reproducible on: macOS 12.4 (Intel)