Apparently this may have been fixed already in version 6000.5.0a6, as this entry has been added to the release notes:

macOS: Added support for CAMetalDisplayLink on the Mac Player.
It is disabled by default and can be enabled in Player Settings by toggling "Use MetalDisplayLink (Mac Player only)" or by using the environment variable UNITY_USE_METAL_DISPLAY_LINK=1.
Using CAMetalDisplayLink decreases stuttering, improves frame pacing, and makes Time.deltaTime more stable.

I still haven't tested it but I've got my hopes up. Also because in this other reported issue by me (which I believe is a duplicate of this bug report), it said (until for some reason it was deleted), that in 6000.5.0a6 this bug has been fixed:
https://issuetracker.unity3d.com/issues/built-project-stutters-intermittently-when-vsync-is-enabled

This stutter has been happening for 5+ years for me. On different Mac machines and many different MacOS and Unity versions. (It says found in 2021.3.45f1) but I believe this happened in 2020.3 and also 2019.3.

The stutter is very visible with either Vsync ON or setting the Application.targetFramerate to 60.

I believe this is the same bug as this one that I reported a few months ago and is being worked on, it said it was fixed in Unity 6000.5.0a6 but now it just says fix in review again:
https://issuetracker.unity3d.com/issues/built-project-stutters-intermittently-when-vsync-is-enabled

This is the same issue I faced in my project, and I reproduced it in this Unity 2022.3.62f3 example:
https://github.com/HofiOne/Unity-macOS-Scroll-Jitter-Demo

It is unbelievable that this serious issue is still not fixed, as it renders games unenjoyable on macOS.

COME ON! HOW HAS THIS NOT BEEN FIXED YET!!!

I am facing the same issue, its in 6.3 lts also, sadly, I expected unity to have solved this by now 😔

This seems like the same issue I'm having on Windows machine.

For me this issue only reproduces on Build in Windowed mode and with VSync enabled (tripple buffering the worst). The huge stutters feels like Time.timeScale is randomly changing and sometimes staying at 0.

For some context, this was tested on a plugged in laptop with rtx 5070, Laptop monitor (150% scaling, 2560x1600), 2nd monitor (100% scaling, 2560x1440). The issue reproduces on both monitors but 2nd monitor is way more frequent.

We've currently quick fixed the issue by fully removing vSync selection from the build.

Reproduces on a new URP project with Unity versions:
6000.0.61f1
6000.0.57f1
2022.3.21f1

Once again, not sure if this is the same issue, cause this is tagged for Mac only. But the description seems to match.

I was actually trying to find another vsync issue all of the team members are having, where GPU is at 90% when vsync is ON, and is at 15% when vsync is OFF. But was unsuccessful on a minimal project.

I can’t even take gameplay footage of my game without the stutter or launch my game on mac. Hope this will be fixed soon!

This is a critical issue for me. It's very difficult for me to work on my game, because I'm stuck in 2021.1, trying to work around all of its numerous bugs. Upgrading the project to any of the more modern editor versions introduces unbearable MEGASTUTTER, which looks like dozens of frames dropped every few seconds in both editor and player, for no clear reason.

I don't know if this is the same issue but I'm seeing a noticable stutter when running the editor player on Mac. Running an M3 Pro chip and when profiled the CPU is spiking with 100ms > 200ms spend in RenderLoop (99.1% to 99.6% self). Appear to happen every 5000 to 6000 frames roughly.

I've removed everything from the scene and the issue can still be seen from within the profiler.