Steps:
1. Create a project
2. Add Cube and Empty child to it
3. Drag to Project Browser to make a prefab
4. Open Cube in Prefab Mode
5. Invoke Asset Selector of "Anchor Override" on Mesh Renderer component of the Cube
6. Switch to "Self"
7. Choose "Empty GameObject"
==>
Transform has 'ReflectionProbeAnchorManager::kChangeSystem' change interests present when destroying the hierarchy. Interests must be deregistered in Deactivate.

Take a look into attached movie for details