Steps to reproduce:
1. Open the attached project "Case_1307112"
2. Open the device Simulator window from Window->General->Device Simulator
3. In the Screen settings set the untick Auto Rotation
4. Select Landscape Left only
5. Open the only script in the Project->Assets
6. Add space or a comment to recompile the scripts and save it
7. Get back to the editor

Expected results: Screen settings do not reset when recompiling scripts
Actual results: Screen settings reset when recompiling the scripts

Reproducible with: 2019.4.19f1(2.2.4-preview), 2020.2.3f1(2.2.4-preview),
Could not test with:
- Screen settings are not available in 2021.1 and 2021.2
- Device simulator package is not available in 2018.4

Note:
- The video of the problem is in the edit field
- It is expected that it will reset when entering and exiting play mode but not when recompiling scripts